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Hexyl gallate

CAS No. 1087-26-9

Hexyl gallate ( Hexyl 3,4,5-trihydroxybenzoate | Gallic acid hexyl ester )

产品货号. M26248 CAS No. 1087-26-9

Hexyl gallate 是没食子酸的烷基酯衍生物,对恶性疟原虫表现出有效的抗疟活性 (IC50: 0.11 mM)。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥356 有现货
100MG ¥518 有现货
200MG ¥883 有现货
500MG ¥1482 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Hexyl gallate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Hexyl gallate 是没食子酸的烷基酯衍生物,对恶性疟原虫表现出有效的抗疟活性 (IC50: 0.11 mM)。
  • 产品描述
    Hexyl gallate, an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).(In Vitro):Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) inhibits only Rhl-dependent production of rhamnolipid and pyocyanin by inhibiting RhlR, without affecting elastase production and biofilm formation which are regulated by the Las system.Hexyl gallates inhibits pigment production at 10-30?μM, but also exhibited antibacterial activity. Hexyl gallates also exhibits antibacterial activity against CV026 cells. Hexyl gallates inhibits only N-butanoyl homoserine lactone (BHL) production at 100 and 300?μM without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1?H) quinolone (PQS) production.Hexyl gallates, an antimicrobial alternative to copper compounds, inhibits Xanthomonas citri growth in a dose-response manner, showing a more pronounced activity at the range of 30-50 μg/ml, and it targets the membrane of X. citri.
  • 体外实验
    Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) inhibits only Rhl-dependent production of rhamnolipid and pyocyanin by inhibiting RhlR, without affecting elastase production and biofilm formation which are regulated by the Las system.Hexyl gallates inhibits pigment production at 10-30?μM, but also exhibited antibacterial activity. Hexyl gallates also exhibits antibacterial activity against CV026 cells. Hexyl gallates inhibits only N-butanoyl homoserine lactone (BHL) production at 100 and 300?μM without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1?H) quinolone (PQS) production.Hexyl gallates, an antimicrobial alternative to copper compounds, inhibits Xanthomonas citri growth in a dose-response manner, showing a more pronounced activity at the range of 30-50 μg/ml, and it targets the membrane of X. citri.
  • 体内实验
    ——
  • 同义词
    Hexyl 3,4,5-trihydroxybenzoate | Gallic acid hexyl ester
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    PEGs
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1087-26-9
  • 分子量
    254.282
  • 分子式
    C13H18O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 41.67 mg/mL (163.87 mM)
  • SMILES
    CCCCCCOC(=O)c1cc(O)c(O)c(O)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
产品手册
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